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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1932 1
1946 1
1959 1
1963 2
1964 1
1966 2
1967 2
1969 2
1970 2
1971 1
1972 3
1973 4
1974 3
1975 18
1976 9
1977 14
1978 18
1979 17
1980 17
1981 18
1982 19
1983 17
1984 35
1985 12
1986 26
1987 20
1988 29
1989 31
1990 38
1991 33
1992 45
1993 42
1994 49
1995 60
1996 54
1997 63
1998 61
1999 56
2000 60
2001 61
2002 75
2003 72
2004 69
2005 91
2006 80
2007 81
2008 86
2009 77
2010 69
2011 72
2012 94
2013 99
2014 80
2015 87
2016 103
2017 86
2018 98
2019 91
2020 109
2021 99
2022 112
2023 101
2024 37

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2,656 results

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Page 1
β(2)-microglobulin amyloidosis.
Corlin DB, Heegaard NH. Corlin DB, et al. Subcell Biochem. 2012;65:517-40. doi: 10.1007/978-94-007-5416-4_19. Subcell Biochem. 2012. PMID: 23225015 Review.
It seems plausible that domain-swapped beta(2)m dimers act as building blocks of beta-spine cross-beta -sheet fibrils consisting of otherwise globular, roughly natively folded protein. An activated complement system and cellular activation perpetuate these reactions which …
It seems plausible that domain-swapped beta(2)m dimers act as building blocks of beta-spine cross-beta -sheet fibrils consisting of otherwis …
Destroying pathogen-tumor symbionts synergizing with catalytic therapy of colorectal cancer by biomimetic protein-supported single-atom nanozyme.
Wang X, Chen Q, Zhu Y, Wang K, Chang Y, Wu X, Bao W, Cao T, Chen H, Zhang Y, Qin H. Wang X, et al. Signal Transduct Target Ther. 2023 Jul 21;8(1):277. doi: 10.1038/s41392-023-01491-8. Signal Transduct Target Ther. 2023. PMID: 37474504 Free PMC article.
This strategy was achieved by a groundbreaking protein-supported copper single-atom nanozyme (BSA-Cu SAN) which was inspired by the structures of native enzymes that are based on protein, with metal elements as the active center. ...
This strategy was achieved by a groundbreaking protein-supported copper single-atom nanozyme (BSA-Cu SAN) which was inspired by the s …
Bioorthogonal Chemistry—Introduction and Overview [corrected].
Carell T, Vrabel M. Carell T, et al. Top Curr Chem (Cham). 2016 Feb;374(1):9. doi: 10.1007/s41061-016-0010-x. Epub 2016 Feb 1. Top Curr Chem (Cham). 2016. PMID: 27572992 Review.
Bioorthogonal chemistry has emerged as a new powerful tool that facilitates the study of structure and function of biomolecules in their native environment. A wide variety of bioorthogonal reactions that can proceed selectively and efficiently under physiologically relevan …
Bioorthogonal chemistry has emerged as a new powerful tool that facilitates the study of structure and function of biomolecules in their …
Probing heavy metal binding to phycobiliproteins.
Bellamy-Carter J, Sound JK, Leney AC. Bellamy-Carter J, et al. FEBS J. 2022 Aug;289(15):4646-4656. doi: 10.1111/febs.16396. Epub 2022 Feb 22. FEBS J. 2022. PMID: 35156751 Free PMC article.
Although the overall quenching ability metal ions have on phycobiliproteins is known, the mechanism of heavy metal binding to phycobiliproteins is not fully understood, limiting their widespread quantitative applications. Here, we show using high-resolution native mass spe …
Although the overall quenching ability metal ions have on phycobiliproteins is known, the mechanism of heavy metal binding to phycobiliprote …
Molybdenum-Copper Antagonism In Metalloenzymes And Anti-Copper Therapy.
Maiti BK, Moura I, Moura JJG. Maiti BK, et al. Chembiochem. 2024 Mar 15;25(6):e202300679. doi: 10.1002/cbic.202300679. Epub 2024 Jan 25. Chembiochem. 2024. PMID: 38205937 Review.
Several models were synthesized to understand the structure-function relationship of these native enzymes. However, this interaction was first observed in ruminants, and they convert molybdate (MoO(4) (2-) ) into tetrathiomolybdate (MoS(4) (2-) ; TTM), reacting with cellul …
Several models were synthesized to understand the structure-function relationship of these native enzymes. However, this interaction …
Screening of native tropical trees for phytoremediation in copper-polluted soils.
Asensio V, G Flórido F, Ruiz F, Perlatti F, Otero XL, Ferreira TO. Asensio V, et al. Int J Phytoremediation. 2018;20(14):1456-1463. doi: 10.1080/15226514.2018.1501341. Epub 2019 Jan 17. Int J Phytoremediation. 2018. PMID: 30652533
Due to the limited number of studies on phytoremediation using native tree species in tropical soils, the aim was to identify new phytoremediator species from tropical climate with the purpose of promoting an increase in the diversity of tropical native trees used i …
Due to the limited number of studies on phytoremediation using native tree species in tropical soils, the aim was to identify new phy …
Native top-down mass spectrometry provides insights into the copper centers of membrane-bound methane monooxygenase.
Ro SY, Schachner LF, Koo CW, Purohit R, Remis JP, Kenney GE, Liauw BW, Thomas PM, Patrie SM, Kelleher NL, Rosenzweig AC. Ro SY, et al. Nat Commun. 2019 Jun 17;10(1):2675. doi: 10.1038/s41467-019-10590-6. Nat Commun. 2019. PMID: 31209220 Free PMC article.
Here we utilize nanodiscs coupled with native top-down mass spectrometry (nTDMS) to determine the copper stoichiometry in each pMMO subunit and to detect post-translational modifications (PTMs). These results indicate the presence of a mononuclear copper cent …
Here we utilize nanodiscs coupled with native top-down mass spectrometry (nTDMS) to determine the copper stoichiometry in each …
Electron transfer and reaction mechanism of laccases.
Jones SM, Solomon EI. Jones SM, et al. Cell Mol Life Sci. 2015 Mar;72(5):869-83. doi: 10.1007/s00018-014-1826-6. Epub 2015 Jan 9. Cell Mol Life Sci. 2015. PMID: 25572295 Free PMC article. Review.
Substrate oxidation occurs near the T1, and electrons are transferred approximately 13 A through the protein via the Cys-His pathway to the T2/T3 trinuclear copper cluster (TNC), where dioxygen reduction occurs. This review outlines the electron transfer (ET) process in la …
Substrate oxidation occurs near the T1, and electrons are transferred approximately 13 A through the protein via the Cys-His pathway to the …
Conformational and functional changes of the native neuropeptide somatostatin occur in the presence of copper and amyloid-beta.
Han J, Yoon J, Shin J, Nam E, Qian T, Li Y, Park K, Lee SH, Lim MH. Han J, et al. Nat Chem. 2022 Sep;14(9):1021-1030. doi: 10.1038/s41557-022-00984-3. Epub 2022 Jul 11. Nat Chem. 2022. PMID: 35817963
Here we report the discovery that conformational and functional changes of a native neuropeptide, somatostatin (SST), occur in the presence of copper ions, metal-free amyloid-beta (Abeta) and metal-bound Abeta (metal-Abeta) found as pathological factors in the brain …
Here we report the discovery that conformational and functional changes of a native neuropeptide, somatostatin (SST), occur in the pr …
Site-Selective Labeling of Native Proteins by a Multicomponent Approach.
Chilamari M, Purushottam L, Rai V. Chilamari M, et al. Chemistry. 2017 Mar 17;23(16):3819-3823. doi: 10.1002/chem.201605938. Epub 2017 Feb 27. Chemistry. 2017. PMID: 28177162
Chemical functionalization of proteins is an indispensable tool. Yet, selective labeling of native proteins has been an arduous task. The limited success of chemical methods allows N-terminus protein labeling, but the examples with side-chain residues are rare. ...
Chemical functionalization of proteins is an indispensable tool. Yet, selective labeling of native proteins has been an arduous task. …
2,656 results